化工进展2012，Vol.31Issue(3)：633-638,6.
微生物转化生产2-苯乙醇的原位产物转移技术研究进展
In situ product removal used in 2-phenylethanol production by microbial conversion
摘要
Abstract
2-phenylethanol（2-PEA）is an aromatic alcohol with rose fragrance,which has been widely used as an essence component in fine chemical and food industries.Compared with the low quality 2-PEA by chemical synthesis and the low yield and high price 2-PEA by plant extraction,2-PEA production by microbial conversion has been increasingly valued,but the product inhibition of 2-PEA to microbes is a problem.In situ product removal（ISPR）techniques can effectively improve 2-PEA yield by reducing product inhibition.The progress of ISPR techniques used in 2-PEA production by microbial conversion was introduced including the extraction,adsorption and membrane-based pervaporation and penetration extraction.The combination of ISPR techniques,high-efficient fermentation process and strain screening for high yield,the development of relatively simple instruments and post-processing techniques are suggested to be the research focus,so as to significantly improve the yield of 2-PEA and realize the industrialization of 2-PEA production by microbial conversion.关键词
微生物转化法/2-苯乙醇/原位产物转移技术Key words
microbial conversion/2-phenylethanol/in situ product removal分类
生物科学引用本文复制引用
李会静,于炜婷,戴小敏,刘袖洞,马小军..微生物转化生产2-苯乙醇的原位产物转移技术研究进展[J].化工进展,2012,31(3):633-638,6.基金项目
国家重点基础研究发展计划 （）
国家自然科学基金 （）
“十一五”国家科技支撑计划 （）
大连市青年科技人才基金（2007J23JH036）项目 （）
