解放军医学杂志2012，Vol.37Issue(3)：200-203,4.
小鼠精子顶体发生的形态学研究
Morphological study of sperm acrosome development in mice
摘要
Abstract
Objective To investigate the characteristics of the morphological changes in acrosome development during the spermiogenesis of mice, and to provide the basis for further studies of the effects of acrosome on the male reproductive function. Methods Periodic-acid Schiff (PAS) staining was used to identify the seminiferous epithelium in the different stages of the spermatogenic cycle of mice testicle under light microscope. The characteristics in the morphological changes in the spermatid acrosome in different phases were observed. Results According to the criterion of the time phase of seminiferous epithelium as proposed by Clermont and Russell, the cycle of the seminiferous epithelia could be divided into 12 stages. The acrosome had their respective characteristics in each stage, which reflect the entire processes of mice sperm acrosome development. Conclusions The characteristics of the morphological changes during the processes of mice sperm acrosome development in different phases can be observed with a light microscope. It can provide the morphological basis for further studies on the impact of all factors on\acrosome development and sperm function, and on the mechanism of acrosome development. This research can also provide experimental evidence for further studies on the effects of acrosome on male reproductive function, and provides a powerful parameter for the clinical evaluation of male fertility.关键词
精子/顶体/生精上皮Key words
spermatozoa/ acrosome/ seminiferous epithelium分类
医药卫生引用本文复制引用
田洪艳,李质馨,王弘珺,林冬静,刘忠平,潘晓燕,李宏宇,窦肇华..小鼠精子顶体发生的形态学研究[J].解放军医学杂志,2012,37(3):200-203,4.基金项目
吉林省教育厅"十一五"科技研究项目(2007433,2008400) （2007433,2008400）
