临床神经外科杂志2012，Vol.9Issue(2)：97-100,4.DOI:10.3969/j.issn.1672-7770.2012.02.012
强化胰岛素疗法在脑卒中治疗中的作用:Meta分析
Intensive versus conventional insulin therapy in stroke (a Meta-analysis)
祁磊 1王茂德 1何百祥 1刘欣 1李奇 1王拓1
作者信息
- 1. 710061 西安交通大学医学院第一附属医院神经外科
- 折叠
摘要
Abstract
Objective To evaluate the effects of intensive insulin therapy ( IIT) and conventional insulin therapy ( CIT) in stroke patients management. Methods ,We systematically searched databases of Chinese and non-Chinese literatures for randomized controlled trial (RCT). The outcome parameters included mortality, late neurological severity scale (NSS) and hypoglycemia episodes. Results Eleven studies were retrieved eventually. The pooled OR of mortality is 0. 85 (95% CIO. 53, 1.36;P=0.50). The pooled OR of NSS is 1.00 (95% CI0.78, 1.29; P = 0.99). The pooled OR of hypoglycemia episodes is 7. 81 (95% CI 5. 17, 11.80,P <0.00 001) with significance statistically. Conclusions In the management of stroke, there were no significant changes between IIT and CIT. However, IIT resulted a much higher hypoglycemia prevalence.关键词
脑卒中/胰岛素/meta分析Key words
stroke/ insulin/ meta-analysis分类
医药卫生引用本文复制引用
祁磊,王茂德,何百祥,刘欣,李奇,王拓..强化胰岛素疗法在脑卒中治疗中的作用:Meta分析[J].临床神经外科杂志,2012,9(2):97-100,4.
