宁夏大学学报（自然科学版）2012，Vol.33Issue(1)：75-78,4.
奶牛乳腺炎与P物质和肥大细胞的相关性研究
Relevancy of the Dairy Cow Mastitis and Substance P and Mast Cells
摘要
Abstract
The changes of the number, activities of mast cells and the dynamic changes of the expression level of substance P at different positions during different periods of pathological changes in dairy cows were investigated with the applied histology, histochemistry and immunohistochemistry. The results showed that a great number of inflammatory cells in the mammary tissue during mastitis influenced lobular interstitial tissue, aliveoli and interstice of glandular epithelial cells, cavities of aliveoli, mammary ducts and inner walls of blob vessels. With prolongation of the course of disease, the inflammatory cells at different positions of mammary glands increased rapidly with the further rising trend, which the difference was significantly compared the normal mammary glands (P<0. 01) to the highest at the bases of breasts (mastitis for 3 months). The number of inflammatory cells at the bases of breasts and the main bodies of breasts were significantly compared to those at the nipple parts (P<0. 01). The structure of aliveoli confused gradually and the blood vessels in the lobules broke out and appeared cracks. At the same time, the changes of mucous mast cells and degranulation at different positions of mammary glands corresponded to the changes of the influences of inflammatory cells, and the neural fibers of SP were also related to the mast cells. The conclusion was that the substance P and the mast cells participated the pathological course of mastitis.关键词
奶牛/乳腺炎/肥大细胞/P物质Key words
dairy cows/ mastitis/ mast cells/substance P分类
生物科学引用本文复制引用
陈健茂,于洪川,王克新..奶牛乳腺炎与P物质和肥大细胞的相关性研究[J].宁夏大学学报（自然科学版）,2012,33(1):75-78,4.基金项目
国家自然科学资金资助项目(8160482) （8160482）
宁夏大学自然基金资助项目(NDZR09-15) （NDZR09-15）
