农药学学报2012，Vol.14Issue(2)：131-135,5.DOI:10.3969/j.issn.1008-7303.2012.02.03
吡啶联三唑类衍生物的合成及杀虫活性
Synthesis and insecticidal activity of a series of novel substituted pyridine linked triazole derivatives
许天明 1姬文娟 1蔡飞 2邢家华 1孔小林1
作者信息
- 1. 浙江省化工研究院,国家南方农药创制中心浙江基地,杭州310023
- 2. 浙江工业大学化学工程与材料学院,杭州310014
- 折叠
摘要
Abstract
l-(2-chloropyridin-3-yl)-5-methyl-lH-l ,2,3-triazole-4-carbonyl chloride (5) was synthesized using 2-chloropyridine as raw materials by diazotization, azide substitution, cyclization, and acyl chlorination. Then 13 novel title compounds were synthesized by acylation of (5) with substituted anilines. The structures of the compounds were confirmed by LC-MS and 'H NMR. The bioassay showed that all the compounds exhibit some insecticidal activity at concentration of 500 mg/L, among them,the mortality ratio of some compounds against Mythimna separate were 100%. While among the compounds , except the mortality ratio of ZJ-7 compounds against Mythimna separate were 100% at concentration of 100 mg/L, the mortality ratio of of the most compounds decreased significantly at concentration of 100 mg/L,some compounds even have no insecticidal activity .关键词
吡啶/联三唑/合成/杀虫活性Key words
pyridine/ 1,2,3 -triazole/ synthesis/ insectical bioactivity分类
化学化工引用本文复制引用
许天明,姬文娟,蔡飞,邢家华,孔小林..吡啶联三唑类衍生物的合成及杀虫活性[J].农药学学报,2012,14(2):131-135,5.
