日用化学工业2011，Vol.41Issue(6)：462-464,3.
反相高效液相色谱法测定化妆品中羟基喹啉
Determination of hydroxyquinoline in cosmetics by reversed- phase high performance liquid chromatography
摘要
Abstract
A reversed - phase high performance liquid chromatographic method was developed for the determination of hydroxyquinoline in cosmetics. The determination process was carried out on a Kromasil C18 column,using a mixture composed of methanol and 0.01 mol/L aqueous solution of sodium decyl sulfonate with pH adjusted to 2. 25 by phosphoric acid at a volume ratio of 62:38 as mobile phase for isocratic elution. The flow rate was 1. 0 mL/min and the column temperature was 25 °C. Detection was carried out at 240 nm. The limit of detection is 2. 254 (Xg/g. The linear plot ranges between 1. 0 and 100. 0 jxg/mL. Average spiked recoveries are 95. 5% ~ 100. 1% with the relative standard deviations of 0. 07% ~ 2. 18%.关键词
化妆品/羟基喹啉/反相高效液相色谱法/测定Key words
cosmetics/ hydroxyquinoline/ reversed - phase high performance liquid chromatography/ determination分类
化学化工引用本文复制引用
张鹏祥,刘洋,高晓譞,徐梦晴,张严赛,赵华..反相高效液相色谱法测定化妆品中羟基喹啉[J].日用化学工业,2011,41(6):462-464,3.基金项目
国家食品药品监督管理局专项资助项目[2010] （）
