四川理工学院学报：自然科学版2012，Vol.25Issue(1)：22-26,5.
多巴胺D3R蛋白同源模建及其应用
Dopamine 3 Receptor Homology Model and Its Application
马丽英 1徐四川2
作者信息
- 1. 凯里学院环境与生命科学学院,贵州凯里556011
- 2. 云南大学化学科学与工程学院,昆明650091
- 折叠
摘要
Abstract
With the crystal structure of Rhodopsin （resolution： 2. 2 A） as a template, D3R protein was modeled by homology modeling. Erythrina molecules were docked into the modeled protein D3R. With the ligand molecule selected as a centroid, a spatial dimension with a radius of 6 A was selected in the docked D3R protein. Binding energy or repulsive energy was calculated between all amino acid residues and ligand molecules in the spatial dimension. Active sites for Erythrina molecules binding to the D3R protein have been found basing on the calculated binding energies.关键词
同源模建/分子对接/多巴胺第三受体Key words
Homology model/molecule docking/Dopamine 3 receptor分类
化学化工引用本文复制引用
马丽英,徐四川..多巴胺D3R蛋白同源模建及其应用[J].四川理工学院学报：自然科学版,2012,25(1):22-26,5.
