氧自由基对内皮祖细胞的损伤及槲皮素的保护作用OACSTPCD
Effects of quercetin on proliferation of human endothelial progenitor cells
目的 研究氧自由基对内皮祖细胞(endothelial progenitor cells,EPCs)的损伤及槲皮素(quercetin,Que)的保护作用.方法 分离并诱导分化人脐血EPCs,随机分为对照组、过氧化氢(H2O2)组:加入500μmol/L的H2O2建立氧化应激损伤EPCs模型、Que干预组:先分别加入浓度为60μmol/L、90μmol/L、120μmol/L的Que预处理30min后,后加500μ mol/L H2O2共同培养.…查看全部>>
Objective To investigate the possible mechanism of the injury induced by oxygen free radical to endothelial progenitor cells ( EPCs) , and the protective effects of quercetin ( Que) on EPCs. Methods Separated EPCs from the human umbilical cord blood, and induced the cells to differentiate. The cells then were randomly assigned into 3 groups:the control group% H2O2 group.(H2O2 500jtmol/L to model oxidative stress injury on EPCs) %Que group (Que60junol/L,90fju…查看全部>>
王艳;胥光热;彭永权;刘应才
泸州医学院附属医院心内科,四川泸州646000遂宁市中心医院心内科,四川遂宁629000泸州医学院附属医院心内科,四川泸州646000泸州医学院附属医院心内科,四川泸州646000
医药卫生
槲皮素氧化应激内皮祖细胞增殖
quercetinoxidative stressendothelial progenitor cells proliferation
《四川医学》 2012 (3)
386-388,3
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