四川医学2012，Vol.33Issue(3)：426-428,3.
儿童急性淋巴细胞白血病诱导化疗期间院内感染20例
Nosocomial infection in 20 children with acute lymphoblastic leukemia during induction chemotherapy
李丹 1史宏 1李蕙 1周敏 1徐鸣 1刘文丽 1邝平兰1
作者信息
- 1. 成都市妇女儿童中心医院儿内1科,四川成都610091
- 折叠
摘要
Abstract
Objective To explore the clinical characteristics of nosocomial infection in children with acute lymphoblastic leukemia during induction chemotherapy, and provide the experience of treatment. Methods The clinical data of 20 children with ALL suffered nosocomial infection during inducting chemotherapy were analyzed. Results Nosocomial infection rate was 95% , the skin and mucosa , and the respiratory tract were the most frequently sites infected, the most common causal organism was gram-negative bacteria; when absolute neutrophil count =￡0. 2 * lO'/L, the infection occoured early , and the fever duration was long. All infected children had been administrated broad spectrum antibiotics, and 7 children infected fungus; of 20 children, one droped out ,the infections in the remain 18 children had been controlled , and 19 children gained remission. Conclusion The marrow remission rate was high giving National ALL Protocol 2006 induction chemotherapy,but the nosocomial infection rate was also high, the infection was severe,with high infection of fungus. The survival could be improved through timely and effective anti-infection treatment.关键词
儿童/急性淋巴细胞白血病/诱导化疗,院内感染Key words
children/ acute lymphoblastic leukemia/ inducting chemotherapy/ nosocomial infection分类
医药卫生引用本文复制引用
李丹,史宏,李蕙,周敏,徐鸣,刘文丽,邝平兰..儿童急性淋巴细胞白血病诱导化疗期间院内感染20例[J].四川医学,2012,33(3):426-428,3.
