摘要
Abstract
Objective To investigate the relationship of atherogenic index of plasma( AIP) to ankle brachial index( ABI) in patients with type 2 diabetes. Methods 143 subjects with type 2 diabetes were included, ankle brachial index, height, weight, blood lipid, acidum uricum.creatinine, HbAlc, urine albumin to crean'nine( ACR) were measured and AIP( log(TG/ HDL-c) ) was calculated. The subjects were divided into two groups according to ABI: ABI?0.9 and 0.9 < ABI < 1.4. Results ? There was significant difference in AIP, TG, HDL-c, LDL-c, sCRP, ACR(P <0.05) between the two groups. ?HDL-c was inversely related to ABI. AIP, TG.TC.LDL, SCRP, ACR were positively related to ABI(P <0.05). The orrelation coefficient of ABI and AIP was 0.484. ?Multivariate analysis by linear regression showed that AIP (P < 0. 000 ) , ACR ( P < 0.000 ) , sCRP ( P < 0. 000) were included. Conclusion In patients with type 2 diabetes, AIP is an important risk factor in pathogenesis and progress of peripheral arterial disease.关键词
2型糖尿病/血浆致动脉硬化指数/踝肱指数Key words
type 2 diabetes mellitus/atherogenic index of plasma/ankle brachial index分类
医药卫生
