四川医学2012，Vol.33Issue(4)：674-675,2.
多烯磷脂酰胆碱联合二甲双胍治疗非酒精性脂肪肝的临床观察
Curative effects of polyene phosphatidyl choline in combination with metformin on non-alcoholic fatty liver disease
肖霞 1吴剑1
作者信息
- 1. 攀枝花市攀钢总医院内科,四川攀枝花617000
- 折叠
摘要
Abstract
Objective To explore the clinical effects of polyene phosphatidyl choline in combination with metformin on non-alcoholic fatty liver disease ( NAFLD) . Methods Sixty patients with NAFLD were randomly divided into 2 groups to the mum-ber table method; treatment group ( n = 30) and control group ( n = 30 ) . The patients in control group only received polyene phos phatidyl choline, but the patients in treatment group were treated with polyene phosphatidyl choline in combination with metformin. The levels of alanine transaminase( AIT) ,aspartate aminotrasferase( AST) ,triglyceride(TG)and total cholesterol( TC) were determined before treatment and after treatment and clinieal curative effect in after treatment. Any other iiver function-protecting and lipid-lowering drugs were excluded during the treatment period. Results Compared with the control 1 iver function, blood 1 ipid profiles were significantly improved in treatment group ( P < 0. 05 ). The total effective rate of clinical efficacy in treatment group (76. 6% )was higher than that in control group(63. 3% ) (P <0. 05). Conclusion Polyene phosphatidyl choline combined with metformin has remarkable curative effects on NAFLD.关键词
非酒精性脂肪肝/多烯磷脂酰胆碱/二甲双胍/疗效Key words
non-alcoholic fatty liver disease/ polyene phosphatidyl choline/ metformin/ curative effect分类
医药卫生引用本文复制引用
肖霞,吴剑..多烯磷脂酰胆碱联合二甲双胍治疗非酒精性脂肪肝的临床观察[J].四川医学,2012,33(4):674-675,2.
