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止痛消结丸对乳腺增生病模型大鼠血清MDA、PRL的影响

蔡国良 张剑桥 马黎 马拴全 胡春玲

山东中医药大学学报2012,Vol.36Issue(2):146-147,149,3.
山东中医药大学学报2012,Vol.36Issue(2):146-147,149,3.

止痛消结丸对乳腺增生病模型大鼠血清MDA、PRL的影响

Effects of Zhitong Xiaojie pills on serum MDA and PRL of rats with mammary glands hyperplasia

蔡国良 1张剑桥 1马黎 1马拴全 2胡春玲1

作者信息

  • 1. 陕西中医学院,陕西咸阳712046
  • 2. 陕西中医学院附属医院,陕西咸阳712083
  • 折叠

摘要

Abstract

Objectives:To observe the effects of Zhitong Xiaojie(ZTXJ) pills on rats with mammary glands hyperpla-sia(MGH) and explore the treating mechanism. Methods:Total 70 rats were randomly divided into seven groups. The estrogen and progesterone were used to establish MGH models(except the blank group). To observe the effects of ZTXJ pills on the malondialdehyde(MDA) and prolactin(PRL). Results:Compared with the control group,serum MDA and PRL were significantly decreased in model group. Compared with model group,serum MDA and PRL were significantly decreased in the large dosage and medium dosage of ZTXJ pills and Rupixiao group. Results:ZTXJ pills can treat MGH by regulating the levels of MDA and PRL.

关键词

止痛消结丸/乳腺增生病/丙二醛/催乳素/大鼠

Key words

Zhitong Xiaojie pills/mammary glands hyperplasia/malondialdehyde/prolactin/rat

分类

医药卫生

引用本文复制引用

蔡国良,张剑桥,马黎,马拴全,胡春玲..止痛消结丸对乳腺增生病模型大鼠血清MDA、PRL的影响[J].山东中医药大学学报,2012,36(2):146-147,149,3.

基金项目

陕西省教育厅科研项目[编号:陕教研(2009)14号] (2009)

山东中医药大学学报

OACSTPCD

1007-659X

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