山东医药2012，Vol.52Issue(12)：66-68,3.
鲜生地对肝损伤模型大鼠枯否细胞功能的影响
Effect of Fresh Rehmannia on Kupffer cells function during liver injury model
摘要
Abstract
Objective To study the effect of Fresh Rehmannia on Kupffer cells function during liver injury model. Methods Sixty-four rats were randomly 4 groups, the normal control group, the liver injury model group, the Fresh Rehmannia group and the Lactulose group. The first two groups were fed by water, the later two groups were each fed by drugs. To observe their plasma endotoxin, TNF-α,IL-1, ALT and CD68. Reslut The levels of ET, TNF-α, IL-1, ALT were significantly lower in the Fresh Rehmannia group and the Lactulose group than those in the liver injury model group (P < 0.05), CD68 protein expression was lower than the model group. Conclusion The Fresh Rehmannia can alleviate the liver cell injury through decreasing function of Kupffer cells and reducing secretion on inflammatory.关键词
鲜生地/肝损伤模型/枯否细胞/CD68蛋白Key words
Fresh Rehmannia/ liver injury model/ Kupffer cells/ CD68 protein分类
医药卫生引用本文复制引用
房杰,孙兰菊,陈明慧,马量..鲜生地对肝损伤模型大鼠枯否细胞功能的影响[J].山东医药,2012,52(12):66-68,3.基金项目
天津市卫生局中医、中西医结合课题(07083). （07083）
