现代检验医学杂志2012，Vol.27Issue(1)：151-153,157,4.DOI:10.3969/j.issn.1671-7414.2012.01.051
基于生物学变异的质量规范在临床生化质控方案设计中的应用
Application of Quality Specification Based on Biological Variation in Planning Quality Control Strategy of Clinical Biochemistry
尹利民 1胡大春1
作者信息
- 1. 昆明市第一人民医院检验科,昆明650011
- 折叠
摘要
Abstract
Objective To study the application of quality specification based on biological variation in planning quality control strategy of clinical biochemistry. Methods According to the method reported by Westgard, Sigma scores of different goal based on biological variability were calculated in 18 biochemistry test items. The dates of imprecision(CV%) were collected from routine quality control last 6 months (from May 2011 to October 2011). The dates of bias were collected from peer group in Interlaboratory QC Program of Bio-Rad in October 2011. The appropriate quality goal and quality control strategy were selected according to the Sigma scores and the performance of quality control strategy. Results The optimum,desirable and minimum quality specifications based on the biological variation were selected for 7,2 and 6 of 18 biochemistry test I-tems, respectively. The current performance of Ca, Cl and Na cannot meet the minimum quality specification based on biological variation. The specifications of them were selected according to CLIA'88 and German Rilibak,respectively. Conclusion Application of quality specification based on biological variation in different levels make the clinicians understand clearly the maximum error of the results caused by testing process. It will be conducive to the application of test results.关键词
生物学变异/质量控制/质量规范Key words
biological variation/quality control/quality specification分类
医药卫生引用本文复制引用
尹利民,胡大春..基于生物学变异的质量规范在临床生化质控方案设计中的应用[J].现代检验医学杂志,2012,27(1):151-153,157,4.
