实用肝脏病杂志2012，Vol.15Issue(3)：238-240,3.DOI:10.3969/j.issn.1672-5069.2012.03.021
1039例隐源性肝炎患者AMA-M2抗体的筛查
Measurement of anti-mitochondria M2 antibodies in 1039 patients with cryptogenic hepatitis
张玮 1王磊 1王奕 1王俐琼 1杜慧慧 1李青梅1
作者信息
- 1. 200032,上海市,上海中医药大学附属龙华医院
- 折叠
摘要
Abstract
Objective To investigate the presence of AMA -M2 antibodies in 1039 patients with cryptogenic hepatitis. Methods M2 antibodies were tested by ELISA. Results M2 antibodies were detected in 81 (7.9% )of the 1039 patients;Of the 81 cases,57 were female and 24 were male,and the mean age was 53.0 ± 14.8 year old,and 78 patients were diagnosed as PBC;The most common symptoms were fatigue (74.4%,58/78), jaundice (61.5%, 48/78 )and skin itching (37.2% ,29/78); Besides, 39 (50.0% ) patients were with ANA positive,and 14 (18.0%) with anti-SSA/Ro positive. Conclusion On the diagnosis of the disease,the detection of serum antimitochondrial autoantibodies (AMA) is an important indicator. The detection of AMA-M2 is important for early diagnosis of patients with PBC.关键词
隐源性肝炎/原发性胆汁性肝硬化/AMA-M2抗体Key words
Cryptogenic hepatitis/Primary biliary cirrhosis/Anti-mitochondria M2 antibodies引用本文复制引用
张玮,王磊,王奕,王俐琼,杜慧慧,李青梅..1039例隐源性肝炎患者AMA-M2抗体的筛查[J].实用肝脏病杂志,2012,15(3):238-240,3.
