实用医学杂志2012，Vol.28Issue(8)：1273-1275,3.DOI:10.3969/j.issn.1006-5725.2012.08.018
新生儿急性肺损伤时血管紧张素转换酶水平的变化及临床意义
The change of angiotemin-converting enzyme levels and clinical significance in neonatal acute lung injury
梁淑文 1崔其亮1
作者信息
- 1. 510150,广州医学院第三附属医院儿科
- 折叠
摘要
Abstract
Objectives To explore the relationship and clinical significance between angiotensin-converting enzyme (ACE) and neonatal acute lung injury (ALI). Methods Forty-three neonates with ALI were collected in this study, whose blood ACE levels and blood gas were analyzed before treatment and ninty-six hours after being diagnosed with ALI. Forty-three children with pneumonia and forty-three with other diseases were selected as two control groups. Results Serum ACE (SACE) level in ALI group was (67.2 ± 11.4)U/L, when compared with pneumonia group (41.6 ± 15.2 U/L) and other disease group (32.8 ± 14.7)U/L. There was a significant difference in the two groups (P< 0.01). SACE) level was negatively correlated with 01 value(R2 = 0.841 7,y=-0.099 lx + 9.865 5) and was positively correlated with AaDpO2 value (R2= 0.826 6,y=0.098 6x-2.331 1)in children with ALI; SACE level significantly increased after 24 h in the neonates with ALI, stabilized in 24 ~ 72 h, and gradually declined after 72 h. Conclusions When neonates were suffering from ALI, their SACE significantly increased in a short time, and there were certain specific in the ALI.关键词
呼吸窘迫综合征,成人/新生儿/血管紧张素转换酶Key words
Respirotory distress syndrome, adults/ Neonate/ Acute lung injury/ Angiotensin-converting enzyme引用本文复制引用
梁淑文,崔其亮..新生儿急性肺损伤时血管紧张素转换酶水平的变化及临床意义[J].实用医学杂志,2012,28(8):1273-1275,3.
