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局限期小细胞肺癌综合治疗疗效临床对比研究

于潜 王伟力 田大力 李厚文 刘晓岚 徐宝宁 姜文军 方辉 李红媛 刘思洋

实用肿瘤杂志2012,Vol.27Issue(3):283-286,4.
实用肿瘤杂志2012,Vol.27Issue(3):283-286,4.

局限期小细胞肺癌综合治疗疗效临床对比研究

Clinical contrast study on effect of multi-modality therapy for limited small-cell lung cancer

于潜 1王伟力 1田大力 1李厚文 1刘晓岚 1徐宝宁 1姜文军 1方辉 1李红媛 1刘思洋1

作者信息

  • 1. 中国医科大学附属第四医院胸外科,辽宁沈阳110032
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摘要

Abstract

Objective To evaluate the difference of prognosis in limited small-cell lung cancer by different therapy modalities. Methods Forty-eight cases of limited small-cell lung cancer were retrospeetivly analyzed, and the differences in median survival time (MST), progression free time (PFS) and side effects incidence were compared. Results The MST of patients in multi-modality therapy group was better than those in non-standard therapy group (P<0.05). The MST of patients in standard chemotherapy group was also better than those in non-standard chemotherapy group (P<0.05). There was no significant difference between concurrent chemoradiotherapy group and sequence chemoradiotherapy group (P=0.159). The MST of patients in prophylatic cranial irradiation group was better than those without prophylatic cranial irradiation (P<0.05). The PFS of patients in standard multi-modality therapy group was better than those in non-standard therapy group (P<0.05). Conclusion Standard multi-modality therapy may obviously improve the MST and PFS in patients with limited small-cell lung cancer.

关键词

癌,小细胞/综合疗法/药物疗法/放射疗法/预后

Key words

carcinoma,small cell/ combined modality dierapy/ drug therapy/ radiotherapy/ prognosis

分类

医药卫生

引用本文复制引用

于潜,王伟力,田大力,李厚文,刘晓岚,徐宝宁,姜文军,方辉,李红媛,刘思洋..局限期小细胞肺癌综合治疗疗效临床对比研究[J].实用肿瘤杂志,2012,27(3):283-286,4.

实用肿瘤杂志

OACSTPCD

1001-1692

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