武警医学2012,Vol.23Issue(6):512-514,3.
结肠癌组织Med-19的表达及临床意义
Expression of Med-19 proteins in human colon cancer tissue and its signifance
段炜 1笪晨星 1顾勇 1吴秀华 1杨艳 2孟宏涛1
作者信息
- 1. 710054,西安,武警陕西总队医院消化内科
- 2. 710032,西安,第四军医大学西京消化病医院
- 折叠
摘要
Abstract
Objective To detect the expression of Med - 19 in colon cancer and the correlation between Med - 19 expression and pathologic features. Methods The immunohistochemical method was used to detect the expression of Med - 19 in 115 colon cancer samples and their corresponding normal tissues. Results The positive rate of Med - 19 expression was significantly higher in colon cancer tissues than in the matched normal tissues ( P < 0. 05) . The positive rate of Med - 19 expression was higher in Dukes C + D stage and lymph node metastasis colon cancer tissues than in the matched normal tissues (P <0. 05,P <0.01) . The expression of Med - 19 was not related to age, sex, size, or histological differentiation (P > 0. 05) . Conclusions Med - 19 is over - expressed in colon cancer tissues,which might be closely related to clinical biological behaviors.关键词
Med-19/结肠癌/免疫组织化学Key words
Med - 19/ colon cancer/ immunohistochemistry分类
临床医学引用本文复制引用
段炜,笪晨星,顾勇,吴秀华,杨艳,孟宏涛..结肠癌组织Med-19的表达及临床意义[J].武警医学,2012,23(6):512-514,3.