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结肠癌组织Med-19的表达及临床意义

段炜 笪晨星 顾勇 吴秀华 杨艳 孟宏涛

武警医学2012,Vol.23Issue(6):512-514,3.
武警医学2012,Vol.23Issue(6):512-514,3.

结肠癌组织Med-19的表达及临床意义

Expression of Med-19 proteins in human colon cancer tissue and its signifance

段炜 1笪晨星 1顾勇 1吴秀华 1杨艳 2孟宏涛1

作者信息

  • 1. 710054,西安,武警陕西总队医院消化内科
  • 2. 710032,西安,第四军医大学西京消化病医院
  • 折叠

摘要

Abstract

Objective To detect the expression of Med - 19 in colon cancer and the correlation between Med - 19 expression and pathologic features. Methods The immunohistochemical method was used to detect the expression of Med - 19 in 115 colon cancer samples and their corresponding normal tissues. Results The positive rate of Med - 19 expression was significantly higher in colon cancer tissues than in the matched normal tissues ( P < 0. 05) . The positive rate of Med - 19 expression was higher in Dukes C + D stage and lymph node metastasis colon cancer tissues than in the matched normal tissues (P <0. 05,P <0.01) . The expression of Med - 19 was not related to age, sex, size, or histological differentiation (P > 0. 05) . Conclusions Med - 19 is over - expressed in colon cancer tissues,which might be closely related to clinical biological behaviors.

关键词

Med-19/结肠癌/免疫组织化学

Key words

Med - 19/ colon cancer/ immunohistochemistry

分类

临床医学

引用本文复制引用

段炜,笪晨星,顾勇,吴秀华,杨艳,孟宏涛..结肠癌组织Med-19的表达及临床意义[J].武警医学,2012,23(6):512-514,3.

武警医学

OACSTPCD

1004-3594

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