物理学报2012,Vol.61Issue(6):479-484,6.
利用轨迹自动识别方法研究单细胞内表皮生长因子受体的运输
The study of EGFR transport in single cell using an automatic method of trajectory identification
摘要
Abstract
We study the characteristics of motion modes of epidermal growth factor receptor(EGFR) trafficking in single cell,by using the automatic method of trajectory identification which is based on the directional persistence and mean square displacement analysis.Each trajectory of EGFRs is divided into four modes of motion:directional motion,super-diffusion,Brownian motion and sub-diffusion.The corresponding dynamic parameters of different modes of motion are calculated and discussed,providing an insight into intracellular trafficking of receptors.关键词
轨迹识别/胞内运输/表皮生长因子受体/动力学特征Key words
trajectory identification/intracellular transport/epidermal growth factor receptor/dynamic characteristics分类
数理科学引用本文复制引用
李辉,段兆文,窦硕星,王鹏业..利用轨迹自动识别方法研究单细胞内表皮生长因子受体的运输[J].物理学报,2012,61(6):479-484,6.基金项目
国家自然科学基金 ()
国家重点基础研究发展计划(批准号:2009CB930704)资助的课题 ()