中国组织工程研究2012，Vol.16Issue(25)：4697-4700,4.DOI:10.3969/j.issn.1673-8225.2012.25.028
冷冻干燥法制备的β-磷酸三钙多孔生物陶瓷支架
Preparation of porous bio-ceramic beta-tricalcium phosphate scaffolds by freeze-drying technique
摘要
Abstract
BACKGROUND: There are many factors which can influence the rnicrostructures and properties of bio-ceramic scaffolds prepared by the freeze-drying process, such as the slurry solid loading, freezing rate, sintering conditions, and soon OBJECTIVE: To prepare bio-ceramic β-tncalciurn phosphate β-TCP) scaffolds with different morphologies and porosities by adjusting the content of the slurries and analyze the influence factorsMETHODS: The β-TCP scaffolds with different morphologies and porosities were prepared, and then bio-ceramic |3-TCP scaffolds were obtained through freezing, drying and heating Phase analysis, micro structure of the section and porosity of bio-ceramic β-TCP scaffolds were detected by X-ray diffraction scanning electron microscopy and Archimedes drainage method, respectivelyRESULTS AND CONCLUSION: The diffraction peak position of the scaffolds was identical with the standard |3-TCP, the scaffolds without polyvmyl alcohol had the macroscopic lamellar pores and porous ceramic walls, and as the solid longing of slurry was increasing, the pore size and the porosity decreased, scaffolds containing polyvmyl alcohol the lamellar pores gradually changed into the interconnected three-dimensional reticulate pores, and the porosity was improved because of the addition of polyvmyl alcohol It is indicated the morphology and porosity of the bio-ceramic scaffolds prepared using the freeze-drying process can be controlled by adjusting the content of the slurries.关键词
冷冻干燥/β-磷酸三钙/多孔陶瓷/聚乙烯醇/气孔率/生物材料分类
医药卫生引用本文复制引用
王雪涛,李静,左开慧,曾宇平,张保卫..冷冻干燥法制备的β-磷酸三钙多孔生物陶瓷支架[J].中国组织工程研究,2012,16(25):4697-4700,4.基金项目
上海市科学技术委员会资助(08DZ2271100) （08DZ2271100）
上海市重点学科建设项目资助(S30206) （S30206）
上海市重点(特色)学科建设项目资助(T0202). （特色）
