畜牧兽医杂志2012，Vol.31Issue(2)：1-5,8,6.
绵羊FecB基因遗传多样性及其产羔数的关联分析
Genetic Diversity of FecB Gene and Association Analysis of Its Litter Size
摘要
Abstract
The Booroola gene（FecB） is a dominant autosomal gene responsible for the fecundity of Booroola Merino sheep with an additive effect on ovulation rate and litter size firstly identified in 1980s.In this study,PCR-SSCP,PCR-RFLP and DNA sequences were used to detect the polymorphism of mononucleotide within FecB gene of 470 sheep including Hu sheep,Small Tailed Han sheep,Wadi sheep,and Altay sheep.And detected whether the FecB gene was the major gene for prolificacy to wadi sheep.The results indicated that these two methods had the identical results and displayed accurately genotyping,good stability and reliability.And the result also showed that the four sheep breeds or strains carried the same FecB mutation（A746G） as found in Booroola Merino sheep.Which is more important,it also proved that FecB gene could be the major gene for prolificacy to wadi sheep.关键词
绵羊/繁殖力/突变Key words
sheep/prolificacy/FecB mutation分类
农业科技引用本文复制引用
李达,孙伟,倪荣,张向楠,张玉龙,储明星,张有法,沈国忠,陈玲,吴文忠,周洪,韩芳,徐厚生..绵羊FecB基因遗传多样性及其产羔数的关联分析[J].畜牧兽医杂志,2012,31(2):1-5,8,6.基金项目
现代肉羊产业技术体系建设 （）
中国博士后科学基金特别资助项目（200902154）、中国博士后科学基金 （）
江苏省自然科学基金BK2007556） （）
江苏省苏北科技发展计划 （）
江苏省高校“青蓝工程”培养基金 （）
苏州市农业科技支撑计划 （）
徐州市农业科技支撑计划 （）
