西南国防医药2012，Vol.22Issue(6)：634-635,2.DOI:10.3969/j.issn.1004-0188.2012.06.025
幽门螺杆菌感染的慢性胃炎患儿细胞因子检测及临床意义
Detection of cytokine in children with chronic gastritis infected by helicobacter pylori and its clinical significance
摘要
Abstract
Objective To detect the peripheral blood interleukin - 2( IL - 2 ), serum soluble IL - 2 receptor( sIL - 2R ), IL - 6 and IL - 8 in children with chronic gastritis correlated with helicobacter pylorii, HP )infection, and to discuss the clinical significance. Methods Totally 84 cases of chronic fastritis were chosen as the case group, and 50 healthy children were chosen as the control group. Their IL - 2,sIL - 2R,IL - 6 and IL - 8 were detected respectively by ELISA and double - antibody sandwich ELISA. Results The IL - 2 levels of the case group were significantly lower than those of the control group( all P <0.01 ),while the levels of sIL - 2R, IL - 6 and IL - 8 were significantly higher than those in the latter group( all P <0. 01 ). Conclusion The cellular immune function is low and disordered in children with chronic gastritis correlated with HP infection. The immune dysfunction plays a certain role in the development of this disease and takes part in the pathological process of gastric mucosal injury.关键词
小儿/幽门螺杆菌/慢性胃炎/细胞因子Key words
children/helicobacter pylori/chronic gastritis/cytokine分类
医药卫生引用本文复制引用
刘文彬,许红波,袁丽..幽门螺杆菌感染的慢性胃炎患儿细胞因子检测及临床意义[J].西南国防医药,2012,22(6):634-635,2.
