疑难病杂志2012，Vol.11Issue(6)：428-430,3.DOI:10.3969/j.issn.1671-6450.2012.06.010
以不明原因发热为主要表现的ANCA相关性小血管炎12例临床分析
Clinical analysis of the ANCA associated vasculitides with unknown reasons fever as main manifestations: A report of 12 cases
林育红 1车向前 1张丽丽1
作者信息
- 1. 110016,沈阳军区总医院呼吸内科/全军呼吸内科及变态反应疾病诊治中心
- 折叠
摘要
Abstract
Objective To explore the clinical features of anti-neutrophil cytoplasmic antibody ( ANCA ) associated vasculitides with fever of unknown origin( FUO ) as main manifestations. Methods Clinical material of 12 cases of ANCA associated vasculitides with FUO as main manifestations were collected. Clinical manifestations, laboratory examination and their diagnostic value were analyzed. Results There were 6 males and 6 females. Mean age was 22 ~78( 55 ±22 ) years old. Fever time from onset to diagnosis confirmation was 22 ~ 65( 38 ± 14 ) days. 12 cases showed varying degree of fever, mainly low to moderate. 8 cases presented with respiratory symptoms. 10 cases presented with renal involvement, expressed as hematuri-a, proteinuria and renal dysfunction. 12 cases had varying degree of anemia ( hemoglobin from 35 to 98g/L ), in which of 3 cases complicated with hemolytic anemia. WBC counts were normal in 6 cases, and higher in 6 cases. The platelet counts were all normal. The plasma albumin level were lower than normal except one case. Conclusion The ANCA associated vasculitides may onset with FUO, without special clinical manifestations. Most cases involve more than one organ system during the course of the disease. Kidney is the most vulnerable organ involved, followed by respiratory system.关键词
不明原因发热/抗中性粒细胞胞浆抗体/小血管炎/临床分析Key words
Fever of unknown origin/ Anti-neutrophil cytoplasmic antibodies/ Vasculitides/ Clinical analysis引用本文复制引用
林育红,车向前,张丽丽..以不明原因发热为主要表现的ANCA相关性小血管炎12例临床分析[J].疑难病杂志,2012,11(6):428-430,3.
