中国骨伤2012，Vol.25Issue(3)：241-245,5.DOI:10.3969/j.issn.1003-0034.2012.03.017
大鼠腰椎亚脱位模型节段活动范围减小的研究
Study on hypomobility of motion segment of rats with lumbar subluxation model
摘要
Abstract
Objective;To observe the basic characteristics of rate with subluxation,which was hypomobility of motion. Methods: One hundred and eight male SD rats (weighted, 350 to 450 g) were randomly divided into experimental group (simple fixation and rotatory fixation) and sham operation group. Each group was subdivided into four groups,including 2,4,8 and 12 weeks sub-groups. Simple fixation and rotatory fixation group were modeled by implanting external linked fixation system; Sham operation group was dealed with operation intervention. At the end of connection,X-ray films was used to observe pos-terier body angle (PBA) ;Spinal stiffness system for stiffness in simple fixation group and rotatory fixation group. Results:Ra-diographic results showed that variation of PBA n experimental groups tended to decrease;and there was no significant difference between simple fixation group and rotatory fixation group at the end of linking time (P>0.05). But there was significant difference between the experimental group and sham operation group (P<0.05). The degree of stiffness showed that the stiffness in experimental group increased with the linking time,but no meaning between groups(P>0.05). Conclusion: Rats with subluxation induced by external linked fixation system can effectively change biomechanical characteristics of spine, reduced the motion with linking time.关键词
大鼠/腰椎/脱位/模型,动物/活动范围,关节Key words
Rats/ Lumbar vertebrae/ Dislocation/ Models, animal/ Range of motion, articular引用本文复制引用
孔令军,程英武,詹红生,元维安,陈博,高乾..大鼠腰椎亚脱位模型节段活动范围减小的研究[J].中国骨伤,2012,25(3):241-245,5.基金项目
国家重点基础研究发展计划("973"计划)基金资助项目(编号:2007CB512701) （"973"计划）
国家杰出青年科学基金资助项目(编号:81025022) （编号:81025022）
国家自然科学基金资助项目(编号:81072891) （编号:81072891）
