局解手术学杂志2012，Vol.21Issue(3)：236-238,3.
CO2气腹对胎鼠脑超微结构和Caspase-3表达的影响
Effects of CO2 pneumoperitoneum on the ultra-structure of rat fetus brain tissue and Caspase-3 expressions
薛翔 1刘青 2周海燕3
作者信息
- 1. 西安交通大学第二医院妇产科,陕西,西安,710004
- 2. 济南市第四人民医院妇产科,山东,济南,250031
- 3. 陕西省妇幼保健院,陕西,西安,710004
- 折叠
摘要
Abstract
Objective To observe the effects of C02 pneumoperitoneum on the ultra-structure of rat fetus brain tissue and Caspase-3 expressions. Methods CO2 pneumoperitoneum was set up under different pressure. The rat fetal brain tissues were taken out on the 17th day of pregnancy within 24 hours. HE staining, immunohistochemistry and electron microscopy were applied to detect the changes in the ultra-structure and the expressions of Caspase-3. Results Slight reversible cell damage was observed in rat fetal brain tissue when the pressure was elevated. There was no significant change in the expression of Caspase-3 in fetal rat brain tissue between the experimental group and the control group ( P >0. 05 ) and the expression of Caspase-3 was also different within the groups ( P >0.05 ). Conclusion The results show that the elevated CO2 pneumoperitoneum can exert slight irreversible damage in rat fetal brain tissue.关键词
CO2气腹/胎鼠脑组织/Caspase-3/大鼠Key words
CO2 pneumoperitoneum/ rat fetus brain tissue/ Caspase-3/ rat分类
医药卫生引用本文复制引用
薛翔,刘青,周海燕..CO2气腹对胎鼠脑超微结构和Caspase-3表达的影响[J].局解手术学杂志,2012,21(3):236-238,3.
