中国康复理论与实践2012，Vol.18Issue(5)：420-422,3.DOI:10.3969/j.issn.1006-9771.2012.05.007
减重步行训练结合电针对脊髓损伤大鼠损伤组织脑源性神经营养因子的影响
Effect of Body Weight Support Treadmill Training and Electroacupuncture on Expression of Brain-derived Neurotrophic Factor in Spinal Cord Injuried Rats
刘帅 1邢艳丽 2孟巍1
作者信息
- 1. 黑龙江中医药大学,黑龙江哈尔滨市,150040
- 2. 黑龙江中医药大学附属第二医院,黑龙江哈尔滨市,150040
- 折叠
摘要
Abstract
Objective To investigate the mechanism of body weight support treadmill training (BWSTT) and electroacupuncture (EA) for spinal cord injury. Methods 56 adult SD rats were divided into control group (n=16), EA group (n=16), BWSTT-EA group (n=16) and blank group (n=8). They were treated 3 d after operation, and assessed with Basso-Beattie-Bresnahan (BBB) scale and the brain-derived neu-rotrophic factor (BDNF) was measured in injured tissue with real time immunohistochemisty assay 1 d, 7 d, 14 d, 21d after treatment. Results The score of BBB was significantly higher in the BWSTT- EA group than in control group and EA group 1 d, 7 d, 14 d, 21 d after treatment (P<0.05), as well as the expression of BDNF (P<0.05). Conclusion BWSTT and EA can promote the recovery of spinal cord injury, which may associate with the expression of BDNF in injured tissue.关键词
脊髓损伤/电针/减重步行训练/脑源性神经营养因子/大鼠Key words
spinal cord injury/ electroacupuncture/ body weight support treadmill training/ brain-derived neurotrophic factor/ rats分类
医药卫生引用本文复制引用
刘帅,邢艳丽,孟巍..减重步行训练结合电针对脊髓损伤大鼠损伤组织脑源性神经营养因子的影响[J].中国康复理论与实践,2012,18(5):420-422,3.
