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轻、中度疼痛对第一、第二躯体感觉皮质激活的功能磁共振成像研究

公维义 薛蕴菁 宋施委 张良成 苏建生 范崇玖

中国康复理论与实践2012,Vol.18Issue(5):423-425,3.
中国康复理论与实践2012,Vol.18Issue(5):423-425,3.DOI:10.3969/j.issn.1006-9771.2012.05.008

轻、中度疼痛对第一、第二躯体感觉皮质激活的功能磁共振成像研究

Primary and Secondary Somatosensory Cortex Activation Induced by Mild and Moderate Pain: A Functional Magnetic Resonance Imaging Study

公维义 1薛蕴菁 2宋施委 3张良成 1苏建生 1范崇玖1

作者信息

  • 1. 福建医科大学附属协和医院麻醉科,福建福州市,350001
  • 2. 福建医科大学附属协和医院核磁共振室,福建福州市,350001
  • 3. 福建医科大学附属协和医院神经外科,福建福州市,350001
  • 折叠

摘要

Abstract

Objective To explore the activation of the primary somatosensory cortex (Si) and secondary somatosensory cortex (Sn) under mild and moderate pain. Methods 7 healthy right-handed volunteers accepted electrostimulation of 1 and 2 times pain threshold respectively. The severity of pain was determined with the Visual Analogue Score (VAS), and they received functional magnetic resonance imaging (fMRI) simultaneously. Results 1 and 2 times pain threshold electrical stimulation caused mild and moderate pain respectively. Both mild and moderate pain activated contralateral S I similarly, and bilateral S n with pain intensity. Conclusion S I and S n respond to the mild and moderate pain in different ways.

关键词

疼痛/电刺激/躯体感觉皮质/功能磁共振成像

Key words

pain/ electrostimulation/ somatosensory cortex/ functional magnetic resonance imaging

分类

医药卫生

引用本文复制引用

公维义,薛蕴菁,宋施委,张良成,苏建生,范崇玖..轻、中度疼痛对第一、第二躯体感觉皮质激活的功能磁共振成像研究[J].中国康复理论与实践,2012,18(5):423-425,3.

基金项目

福建省卫生厅青年基金资助项目(2008-1-23). (2008-1-23)

中国康复理论与实践

OA北大核心CSCDCSTPCD

1006-9771

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