中国康复理论与实践2012，Vol.18Issue(6)：573-576,4.DOI:10.3969/j.issn.1006-9771.2012.06.022
年龄对颈动脉血流动力学影响的初步研究
Effect of Age on Carotid Hemodynamics
摘要
Abstract
Objective To study the effect of age on the hemodynamics of common carotid artery. Methods 47 healthy volunteers were studied. Wall shear stress (WSS) values localized at common carotid artery 2 cm below the bifurcation were calculated with cine phase-contrast MR imaging combined three-dimensional paraboloid (3DP) model. On the spatial distribution, common carotid artery wall was divided into 24 equal parts. Calculate the mean WSS in a cardiac cycle on each part, and choose the minimal WSS value. Then the effects of age on the average WSS and minimal WSS were observed. Results Total 94 common carotid arteries of 47 health volunteers were examined, in which 9 carotid arteries in 9 volunteers were excluded because of uninterpretable high-resolution MRI findings or volunteer's intolerance for the detection. In the remaining 85 common carotid arteries, the average WSS and the minimal WSS during a cardiac cycle on the spatial distribution were (7.45±2.12) dyne/cm2 and (5.98±1.93) dyne/cm2 respectively. Both average WSS and minimal WSS were negative correlated with age (P<0.05). Conclusion With the age increased, mean WSS and minimal WSS on the spatial distribution of common carotid artery decreased.关键词
颈动脉/血流动力学/年龄Key words
carotid/ hemodynamics/ age分类
医药卫生引用本文复制引用
秦海强,赵性泉,周萍,张宁,隋滨滨,王拥军..年龄对颈动脉血流动力学影响的初步研究[J].中国康复理论与实践,2012,18(6):573-576,4.基金项目
1.首都医学发展科研基金资助项目(2009-3106) （2009-3106）
2.北京市科普项目(社会征集类)(Z09020600360917) （社会征集类）
3.首都医科大学基础-临床科研合作基金(11021289 和1000170791). （11021289 和1000170791）
