中国临床医学2012，Vol.19Issue(2)：114-116,3.
肺炎衣原体感染与卒中关系的研究
Chlamydia Pneumonia Infection in Stroke Patients
摘要
Abstract
Objective: To investigate the infection of Chlamydia pneumonia(Cpn) in stroke patients and its relationship with risk factors of stroke. Methods:In this case-control study,120 patients with stroke and 60 healthy controls were tested scrologi-cally for specific Cpn-IgM, Cpn-IgA and Cpn-IgG by enzyme-linked immunoadsorbent assay (KLKSA). Moreover, cholesterol (TO, triacylglyccridc(TG) , high density lipoprotcin( HDL) and low density lipoprotcin(LDL) were also detected. According to pathogencsis and imaging findings of stroke, 120 cases were divided into four groups: cerebral infarction groupCn = 48), transient ischemic attack(TIA) group Cn - 14), cerebral cardiocmbolism groupCn - 29) and hcmatcnccphalon groupCn -29). Results: There were significant differences between cases and controls in TC, TG, HDL, LDL, Cpn-IgA and Cpn-IgG scropos-itivity. Logistic stepwisc regression analysis showed that Cpn-IgA and Cpn-IgG scropositivity were independently associated with atherosclerosis stroke (including cerebral infarction and TIA) , but not with cardiocmbolic or hcmatcnccphalon subtypes. 180 people in this study were divided into Cpn-IgA scropositivity groupCn = 124) and Cpn-IgA scroncgativity groupCn = 56). The levels of scrum TC, TG, LDL in Cpn-IgA scropositivity group were significantly higher than those in Cpn-IgA scroncgativity group. Conclusions: Scrologic positivity of Cpn-IgA and Cpn-IgG is independently related to atherosclerosis stroke. The mechanism is likely to be associated with dyslipidcmia.关键词
肺炎衣原体/卒中/危险因素Key words
Chlamydia pneumonia/ Stroke/ Risk factor分类
医药卫生引用本文复制引用
段磊,任传成,倪冬艳,石蕾..肺炎衣原体感染与卒中关系的研究[J].中国临床医学,2012,19(2):114-116,3.基金项目
上海市闵行区科委基金(编号:MHZ2009-114) （编号:MHZ2009-114）
