中国全科医学2012,Vol.15Issue(8):911-912,2.
血清胱抑素C对老年高血压病肾功能损害诊治的临床意义
Clinical Significance of Serum Cystatin C in Treating Elderly Hypertensive Renal Damage
摘要
Abstract
Objective To study the application value of serum cystatin C ( CysC ) in hypertensive patients with impaired renal function. Methods Tested the levels of serum CysC, Creatinine ( Cr ) and uric acid ( UA ) and made a comparison between CysC and UA in patients with different Cr. Results The difference of CysC in patients with different Cr was significant ( P < 0. 05 ); the difference of UA between the patients with normal Cr and the other three groups was significant ( P < 0. 05 ); the difference of UA between the other three groups was not significant ( P >0. 05 ). In the patients with normal Cr, there were 35 patients with normal CysC, 20 patients with CysC increasing, the difference between them was also significant ( P <0. 05 ). After renal protective treatment such as controlling blood pressure, improving renal blood flow, the levels of Cr and CysC all had an obvious decrease than before ( P <0. 05 ). Conclusion A sensitive endogenous indicator for early hypertensive renal impairment, serum CysC plays a very important role in early diagnosis of hypertensive renal injury, assessment of renal dysfunction and judgment of therapeutic effect.关键词
高血压/肾损害/血清胱抑素C/肌酐/尿酸Key words
Hypertension/Kidney damage/ Serum cystatin C/Creatinine/ Uric acid分类
医药卫生引用本文复制引用
苏增锋,张颖,张杰,吴泽兵..血清胱抑素C对老年高血压病肾功能损害诊治的临床意义[J].中国全科医学,2012,15(8):911-912,2.基金项目
合肥市科技局科研计划项目(2009年度) (2009年度)