摘要
Abstract
Objective To explore the helicobacter pylori ( H. pylori ) infection in patients with diabetes mellitus ( DM ) and to analyze the related factors of carotid atherosclerosis. Methods Totally 227 patients with DM and 436 healthy controls were included in our study, and the H. pylori infections were detected. DM groups was divided into carotid atherosclerosis ( CAS ) group and non - CAS group, we assessed the related factors of CAS in DM patients including blood pressure, blood fat, smoking and H. pylori infection. Results The H. pylori infection rate in DM group ( 63. 78% ) was significantly higher than that in control group ( 52. 06% ). The patients in CAS group had statistically higher age, smoking rate, H. pylori infection rate, systolic blood pressure ( SBP ), diastolic blood pressure ( DBP ), total cholesterol ( TC ), triglyceride ( TG ) and more males as compared with those in non - CAS group, while high density lipoprotein cholesterol ( HDL - C ) was significantly lower than non - CAS group. There was no difference in alcohol consumption and low density lipoprotein cholesterol ( LDL - C ) between the two groups. Logistic regression analysis showed that H. pylori infection rate, smoking, age, SBP, TG, HDL - C were correlated with CAS in DM group, while HDL - C as a protective factors. Conclusion H. pylori infection rate in DM patients is higher than that in healthy individuals, and H. pylori infection rate, smoking, age, SBP, TG, and HDL - C can influence the development of CAS in DM patients.关键词
糖尿病/螺杆菌,幽门/动脉粥样硬化Key words
Diabetes mellitus/ Helicobacter pylori/ Atherosclerosis分类
医药卫生
