摘要
Abstract
Objective To discuss the clinical effects of ambroxol hydrochloride combined with ventolin and budesonide aerosol inhalation on acute exacerbations of chronic obstructive pulmonary disease ( AECOPD ). Methods Sixty AECOPD patients with II degree pulmonary function were randomly divided into groups control ( n = 30, received conventional treatment such as oxygen uptaking, anti - infection drug etc. ) and treatment ( n =30, given ventolin and Budesonide aerosol inhalation based on conventional). Both groups were treated with ambroxol, 30 mg, iv gtt, 3 times/d, 7 d. The clinical effects, clinical remission time of acute dyspnea and hospital stay were observed after therapy. Results After treatment, marked effect was noted in 17 cases, effect in 10 and no effect in 3 in treatment group, while 8, 19, 3 in control group, respectively. The difference was significant ( u = 328. 5, P = 0. 046 ). The clinical remission time of acute dyspnea significantly shorter in treatment group than in control [ ( 4. 30 ± 1. 39 ) d vs ( 5. 73 ±2. 08 ) d, P <0. 05 ] , hospital stay significantly shorter [ ( 8. 70 ±3. 17 ) d vs ( 12. 16 ±3. 97 ) d, P <0. 05 ]. Conclusion Intravenous ambroxol hydrochloride combined with ventolin and budesonide aerosol inhalation has marked effects on AECOPD, with short remission time and hospital stay.关键词
盐酸氨溴索/硫酸沙丁胺醇/布地奈德/肺疾病,慢性阻塞性/急性发作/治疗结果Key words
Ambroxol hydrochloride/ Ventolin/ Budesonide/ Pulmonary disease, chronic obstructive/ Acute exacerbations/ Treatment outcome分类
医药卫生
