首页|期刊导航|中国神经再生研究(英文版)|Paravertebral fascial massage promotes brain development of neonatal rats via the insulin-like growth factor 1 pathway
中国神经再生研究(英文版)2012,Vol.7Issue(15):1185-1191,7.DOI:10.3969/j.issn.1673-5374.2012.15.010
Paravertebral fascial massage promotes brain development of neonatal rats via the insulin-like growth factor 1 pathway
Paravertebral fascial massage promotes brain development of neonatal rats via the insulin-like growth factor 1 pathway
摘要
Abstract
Massage in traditional Chinese medicine can promote body and brain development of premature and normal newborn infants. In the present study, neonatal rats (1 day old) underwent paravertebral fascial massage (15 consecutive days), followed by subcutaneous injection of insulin-like growth factor 1 receptor antagonist, JB1 (9 consecutive days). Paravertebral fascial massage significantly increased insulin-like growth factor 1 expression and cell proliferation in the subventricular zone of the lateral ventricle and dentate gyrus of the hippocampus. However, JB1 inhibited this increase. Results suggest that paravertebral fascial massage can promote brain development of neonatal rats via the insulin-like growth factor 1 pathway.关键词
paravertebral fascial massage/insulin-like growth factor 1/neurogenesis/immunohistochemistry/neural regenerationKey words
paravertebral fascial massage/insulin-like growth factor 1/neurogenesis/immunohistochemistry/neural regeneration引用本文复制引用
Zhongqiu Wen,Wenqin Zeng,Jingxing Dai,Xin Zhou,Chun Yang,Fuhua Duan,Yufeng Liu,Huiying Yang,Lin Yuan..Paravertebral fascial massage promotes brain development of neonatal rats via the insulin-like growth factor 1 pathway[J].中国神经再生研究(英文版),2012,7(15):1185-1191,7.基金项目
This study was supported by the National Basic Research Program of China (973 Program),No.2007CB512705 (973 Program)
the General Program for Youths of the National Nature science Foundation of China,No.30801464. ()