首页|期刊导航|中国神经再生研究（英文版）|Botulinum toxin injection improved voluntary motor control in selected patients with post-stroke spasticity
中国神经再生研究（英文版）2012，Vol.7Issue(18)：1436-1439,4.DOI:10.3969/j.issn.1673-5374.2012.18.011
Botulinum toxin injection improved voluntary motor control in selected patients with post-stroke spasticity
Botulinum toxin injection improved voluntary motor control in selected patients with post-stroke spasticity
摘要
Abstract
The effect of botulinum toxin type A injection on voluntary grip control was examined in a 53-year-old female, who sustained a hemorrhagic right middle cerebral artery stroke 3 years previously, which resulted in finger flexor spasticity and residual weak finger/wrist extension. The patient received 50 units of botulinum toxin type A injection each to the motor points (2 sites/muscle) of the left flexor digitorum superficialis and flexor digitorum profundus, respectively. Botulinum toxin injection led to weakness and tone reduction in the spastic finger flexors, but improved grip release time in grip initiation/release reaction time tasks. Improved release time was accompanied by shortened extensor electromyography activity, and improved release time likely correlated with blocked co-contraction of finger flexors during voluntary finger extension. This case report demonstrated that botulinum toxin injection improved voluntary motor control of the hand in a chronic stroke patient with residual finger extension.关键词
botulinum toxin type A/spasticity/grip/stroke/neural regenerationKey words
botulinum toxin type A/spasticity/grip/stroke/neural regeneration引用本文复制引用
Shuo-Hsiu Chang,Gerald E Francisco,Sheng Li..Botulinum toxin injection improved voluntary motor control in selected patients with post-stroke spasticity[J].中国神经再生研究（英文版）,2012,7(18):1436-1439,4.基金项目
This study was supported in part by NIH grants (NIH/NINDS R01NS060774 （）
NIH/NICHD/NCMRR R24 HD050821-08) under subcontract with the Rehabilitation Insti-tute of Chicago. （）
