中国兽医科学2012，Vol.42Issue(4)：331-338,8.
口蹄疫病毒Mya98谱系猪源及牛源2010年分离株的分子特征及蚀斑显型比较分析
Molecular characteristics and plaque phenotype of Mya98/FMDV isolated from different hosts in 2010
摘要
Abstract
For understanding the molecular characteristics and plaque phenotype of Mya98/FMDV isolated from different hosts in 2010,molecular characteristic analysis and plaque phenotype comparison of 4 foot-and-mouth disease viruses（FMDV） isolated from various hosts were performed.And the result revealed that the isolates were of the swine strain O/CHN/Mya98/2010S2.This strain shared 21 specific amino acid substitution（AAS） sites with bovine strains,which were distributed within the range of the open reading frame（ORF）.The swine strain O/CHN/Mya98/2010S1 also shared a number of similar amino acid sites with bovine strains,and both of the identified strains demonstrated small plaque phenotype.However,swine strain O/CHN/Mya98/2010S2 manifested as a mixture of small and large plaques in the plaque assay,suggesting that the variable site of this strain was of significance to the change in virus plaque phenotype.关键词
O型口蹄疫病毒/Mya98谱系/不同宿主/分子特征/蚀斑显型Key words
FMDV serotype O/Mya98 strain/different host/molecular characterization/plaque phenotype分类
农业科技引用本文复制引用
周强,包慧芳,白兴文,孙普,陈应理,谢宝霞,卢曾军,刘在新..口蹄疫病毒Mya98谱系猪源及牛源2010年分离株的分子特征及蚀斑显型比较分析[J].中国兽医科学,2012,42(4):331-338,8.基金项目
农业行业专项 （）
国家高技术研究发展计划（863）项目 （）
兰州市科技计划项目 （）
