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巨大淋巴结增生症27例临床分析

陈哲 刘竟芳 周雨迁 霍继荣

中国实用内科杂志2012,Vol.32Issue(4):300-302,3.
中国实用内科杂志2012,Vol.32Issue(4):300-302,3.

巨大淋巴结增生症27例临床分析

Castleman's disease:clinical analysis of 27 cases

陈哲 1刘竟芳 1周雨迁 2霍继荣2

作者信息

  • 1. 湖南省长沙市中心医院老年医学科,长沙410004
  • 2. 中南大学湘雅二医院消化内科,长沙410011
  • 折叠

摘要

Abstract

Objective To broaden our horizon with regard to lymphadenomegaly ( Castleman's disease). Methods The clinical profiles of 27 patients with confirmed Castleman's disease (CD) via pathological biopsy in The Second Xiangya Hospital of Central South University from January 1996 to May 2008 were gathered. All patients were assigned to local Castleman's Disease (LCD) group and multicentre Castleman's Disease (MCD) group. Retrospective analyses and reviews were performed on clinical manifestations, histopathologic subtypes and treatment. Results The severity of Castleman's disease was correlated with the responses to treatment, clinical and pathological subtypes. MCD and plasma cell subtype had worse prognosis. Conclusion LCD and MCD are two types of CD with distinct clinical manifestations and prognosis. Regarding the variation in pathogenesis and comorbidities, subtype differential diagnosis is of critical significance.

关键词

巨大淋巴结增生症/病理活检/淋巴瘤

Key words

Castleman's disease/ pathological biopsy/ lymphoma

分类

医药卫生

引用本文复制引用

陈哲,刘竟芳,周雨迁,霍继荣..巨大淋巴结增生症27例临床分析[J].中国实用内科杂志,2012,32(4):300-302,3.

中国实用内科杂志

OA北大核心CSCDCSTPCD

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