中国实用外科杂志2012，Vol.32Issue(4)：300-303,4.
食管胃结合部腺癌围手术期营养支持
Perioperative nutrition support of adenocarcinoma of the esophagogastric junction
王强 1赵毅1
作者信息
- 1. 中国医科大学附属盛京医院胃肠、营养外科,辽宁沈阳110004
- 折叠
摘要
Abstract
The primary treatment of adenocarcinoma of theesophagogastric junction (AEG) is surgery, but more than 50% of curatively resected patients undergo recurrence or cancer-related death during postoperative 5 years. It implies multidisciplinary treatment of radio- and chemotherapy is still necessary. Recently, neoadjuvant therapy has been paid more attention to, and neoadjuvant radiotherapy is currently considered able to improve 5-year overall survival. Moreover, European Organization for Research and Treatment of Cancer has made a consensus guideline of neoadjuvant radiotherapy for AEG, which is useful in clinical practice. Neoadjuvant chemotherapy is meaningful to increase R0 resection rate, but should combine adjuvant chemotherapy to improve overall survival. Concept on adjuvant chemotherapy is according to gastric cancer, and NCCN guideline recommends classic ECF or modified ECF regimens. Results of monotherapy SI trial also showed improved overall survival. The evidence of intra-or postoperative radiotherapy is poor and can not improve long term survival. Therefore, preoperative concurrent chemoradiotherapy plus postoperative chemotherapy is currently preferable multidisciplinary treatment model.关键词
食管胃结合部腺癌/围手术期营养支持/Barrett 食管Key words
adenocarcinoma of esophagogastric junction/ chemotherapy/ radiotherapy/ perioperative peroid/ multidisciplinary therapy分类
医药卫生引用本文复制引用
王强,赵毅..食管胃结合部腺癌围手术期营养支持[J].中国实用外科杂志,2012,32(4):300-303,4.
