中国药房2012，Vol.23Issue(11)：992-994,3.DOI:10.6039/j.issn.1001-0408.2012.11.13
炉甘石炮制工艺及炮制品质量标准研究
Study on the Processing Technology of Calamina and Quality Standard of Processed Product
摘要
Abstract
OBJECTIVE: To optimize the processing technology of Calamina, and to investigate the quality of processed prod-uct. METHODS: The processing technology of Calamina was optimized by central composite design-response surface method using the content of ZnO as index. The dynamic observation of its shape and particle size was conducted to optimize the water grind pro-cessing of Calamina. The apperance,particle size and content of ZnO were investigated. RESULTS: The optimal processing technol-ogy was as follows: drug granularity was sifted by No.2 sieve, calcining 4 h at 400 ℃, adding 5-fold water to grind drug into paste, then adding 40-fold water to stir, resting for above 8 min to pour out the suspension. The number of water grind processing was six times, then the suspension was placed for 21 h before drying at 120 ℃. The processed product was faint red and particle size was lower than 200 mesh. The content of ZnO in processed product was no less than 56%. CONCLUSION: Optimal technolo-gy is suitable for the processing of Calamina.关键词
炉苷石/氧化锌/星点设计-效应面法/炮制工艺/粒径Key words
Calamina/ ZnO/ Central-composite design-response surface methodology/ Processing technology/ Particle size分类
医药卫生引用本文复制引用
张杰红,彭月,施学骄,刘友平..炉甘石炮制工艺及炮制品质量标准研究[J].中国药房,2012,23(11):992-994,3.基金项目
国家中医药管理局中医药行业科研专项中药饮片调剂规范化研究课题(201007011-10) （201007011-10）
