中国药房2012,Vol.23Issue(11):997-998,2.DOI:10.6039/j.issn.1001-0408.2012.11.15
正交试验优选复方鱼腥草颗粒中连翘挥发油β-环糊精包合工艺
Optimization of the β-cyclodextrin Inclusion Technology for Essential Oil of Forsythia suspensa in Compound Yuxingcao Granules by Orthogonal Test
宋宁宁 1许扬彪1
作者信息
- 1. 广西壮族自治区食品药品检验所,南宁530021
- 折叠
摘要
Abstract
OBJECTIVE: To study the inclusion technology for the essential oil of Forsythia suspensa in Compound yuxingcao granules using β-cyclodextrin. METHODS: The inclusion technology was optimized with ratio of β-CD to oil, inclusion time, inclu-sion temperature and ratio of water to β-CD as factors using the yield of essential oil and clathration percentage as index. RE-SULTS: The optimal condition: ratio of essential oil to β-CD was 10 mL:80 g; the process lasted for 4 hours at 60 ℃; 8 times of water respect to β-cyclodextrin was added. CONCLUSION: The technology is proved to be simple, feasible and effective to the dis-sipation of avoid active gradients from essential oil.关键词
复方鱼腥草颗粒/连翘挥发油/β-环糊精/正交试验/包合工艺Key words
Compound yuxingcao granules/ Essential oil of Forsythia suspensa/ β-cyclodextrin/ Orthogonal test/ Inclusion technology分类
医药卫生引用本文复制引用
宋宁宁,许扬彪..正交试验优选复方鱼腥草颗粒中连翘挥发油β-环糊精包合工艺[J].中国药房,2012,23(11):997-998,2.