中国药房2012，Vol.23Issue(12)：1108-1109,2.DOI:10.6039/j.issn.1001-0408.2012.12.19
雷尼替丁联合蒙脱石散外用治疗复发性口腔溃疡的疗效观察
Efficacy Observation of Ranitidine Combined with Montmorillonite in the Treatment of Recurrent Oral Ulcer
郭秀荣 1吴江2
作者信息
- 1. 河北联合大学附属医院感染性疾病科,河北唐山063000
- 2. 解放军第255医院口腔科,河北唐山063010
- 折叠
摘要
Abstract
OBJECTIVE: To observe the therapeutic efficacy of ranitidine combined with montmorillonite in the treatment of recurrent oral ulcer (ROU). METHODS: 138 ROU patients were randomly divided into control group (69 patients) and treatment group (69 patients). Control group was directly applied montmorillonite 5 g locally, 5 to 6 times per day; Treatment group was applied the mixture of montmorillonite 5 g with ranitidine 900 mg after removing capsule, 5 to 6 times per day locally, with oral administration of ranitidine 150 mg per day. The efficacy and ADRs of 2 groups were observed. RESULTS: The duration of symptoms and the whole course of disease of the treatment group were obviously shorter than that of control group. The effective rate of treatment group was 95.7% and that of control group was 65.2%, There was statistical significance (P＜0.01). There was no ADR were found in 2 groups. CONCLUSIONS: The combined treatment of ranitidine and montmorillonite for ROU can quickly relieve the symptoms, promote the ulcer's healing and reduce the relapse, therefore is effective and without ADR.关键词
雷尼替丁/蒙脱石散/口腔溃疡Key words
Ranitidine/ Montmorillonite/ Recurrent oral ulcer分类
医药卫生引用本文复制引用
郭秀荣,吴江..雷尼替丁联合蒙脱石散外用治疗复发性口腔溃疡的疗效观察[J].中国药房,2012,23(12):1108-1109,2.
