中国药房2012，Vol.23Issue(14)：1291-1292,2.DOI:10.6039/j.issn.1001-0408.2012.14.16
我院2005-2010年肺炎克雷伯菌的耐药性变迁及其与抗菌药物临床用量的相关性分析
Drug Resistance and Its Correlation with Clinical Use of Antibiotics of Klebsiella Pneumoniae in Our Hospital from 2005 to 2010
魏建英 1李亮 1袁丽萍1
作者信息
- 1. 青华大学第一附属医院药学部,北京100016
- 折叠
摘要
Abstract
OBJECTIVE: To study the compatible stability of Cefathiamidine for injection with Acyclovir for injection in 0.9% Sodium chloride injection or in 5% Glucose injection. METHODS: Under light, at room temperature (25 ± l)t, the changes of the mixture in appearance and Ph value within 6 h were observed respectively, and the contents of cefathiamidine and acyclovir were determined by HPLC to investigate the generation of new substance. RESULTS: Within 6 hours, the color of the mixture in 0.9% Sodium chloride injection or in 5% Glucose injection became deep gradually. The Ph value and the content of cefathiamidine came down significantly. CONCLUSION: Cefathiamidine for injection can not be mixed with Acyclovir for injection in 0.9% Sodium chloride injection or 5% Glucose injection to use.关键词
肺炎克雷伯菌/耐药性/用药频度/相关性Key words
Cefathiamidine/Acyclovir/Compatibility/Stability/HPLC分类
医药卫生引用本文复制引用
魏建英,李亮,袁丽萍..我院2005-2010年肺炎克雷伯菌的耐药性变迁及其与抗菌药物临床用量的相关性分析[J].中国药房,2012,23(14):1291-1292,2.
