中国药房2012，Vol.23Issue(14)：1295-1299,5.DOI:10.6039/j.issn.1001-0408.2012.14.18
XELOX方案与FOLFOX方案治疗转移性结直肠癌的系统评价
Systematic Review of XELOX Regimen and FOLFOX Regimen for Metastatic Colorectal Cancer
周俊翔 1余文韬 2徐珽 1唐尧3
作者信息
- 1. 四川大学华西医院药剂科,成都610041
- 2. 四川大学华西药学院,成都610041
- 3. 四川大学华西临床医学院,成都610041
- 折叠
摘要
Abstract
OBJECTIVE: To provide a reasonable antibiotic treatment project with accurate efficacy, minor side effects for the adolescent orthodontic patients with gingivitis. METHODS: 103 patients were randomly divided into azithromycin group, amoxicil-lin group and clindamycin group. Aspartate aminotransferase level of the gingival crevicular fluid (GCF-AST) and the clinical effective rate were used as evaluation indexes. RESULTS: Effective rate of amoxicillin group was significantly higher than azithromycin group (P<0.05), there was no statistical significance between other 2 groups (P>0.05) ; the level of GCF-AST in amoxicillin group and clindamycin group after treatment was significantly lower than before (P<0.05); meanwhile, the incidence of adverse drug reactions showed no significant difference among 3 groups (P>0.05). CONCLUSION: Clinical use of antibiotics in descending order of preference is amoxicillin, clindamycin, azithromycin for adolescent patients with gingivitis.关键词
卡培他滨/5-氟尿嘧啶/结直肠癌/Meta分析/系统评价Key words
Adolescent/Gingivitis/Antibiotics/Clinical study分类
医药卫生引用本文复制引用
周俊翔,余文韬,徐珽,唐尧..XELOX方案与FOLFOX方案治疗转移性结直肠癌的系统评价[J].中国药房,2012,23(14):1295-1299,5.
