中国药理学通报2012，Vol.28Issue(4)：581-584,4.DOI:10.3969/j.issn.1001-1978.2012.04.032
两种不同膀胱测压方法对不同年龄大鼠尿动力测定的影响
Comparison of urodynamical differences by two cystometric methods in rats of different ages
摘要
Abstract
Aim To compare the differences of urodynamics index, the advantages and the disadvantages of two kinds of cysto-metric methods, one being that rats placed double catheters through urethra under anesthesia by urethane and the other being that rats set with single one connected with tee. Methods 11adult female rats of 6 months and the other 11 of 12 months were taken and anesthetized by urethane, ip. Two 3F catheters were put in urethra,and connected with the pressure sensor of urody-namic instrument and the micro-injection pump respectively ;ree-tal pressure measuring balloon tube was inserted through anal.connected with abdominal pressure sensor; urodynamic instrument was applied to measure the change of pressure in rat bladder filling phase and the abdomen leak point pressure. Five days later,single 3F catheter was inserted as before, connected with the tee. One end of tee joined with the trace infusion pump,and the other was connected with urinary bladder pressure sensor. The rest of operations were done as previous. Results BLPP, MVP of two group rats had significant difference ( P < 0. 05 )measured with double tube methods,but there was no differencedetermined by the tee methods. Conclusions Both rat urinarybladder pressure methods have the power of some indicators ofsignificant differences, and both methods have advantages anddisadvantages.关键词
大鼠/不同年龄/乌拉坦/尿动力学/不同方法/膀胱测压Key words
rats/ different ages/ urethane/ urodynamics/ different cystometric methods/ bladder pressure measurement分类
医药卫生引用本文复制引用
邝兆进,操红缨,黄萍,吴清和..两种不同膀胱测压方法对不同年龄大鼠尿动力测定的影响[J].中国药理学通报,2012,28(4):581-584,4.基金项目
国家自然科学基金资助项目(No 30873425) （No 30873425）
