中国医学科学院学报2012，Vol.34Issue(2)：178-182,5.DOI:10.3881/j.issn.1000-503X.2012.02.015
细胞因子信号转导抑制因子3的研究进展
Research Advances in Suppressor of Cytokine Signaling 3
摘要
Abstract
Suppressor of cytokine signaling (SOCS) 3, a novel type of cytokine signal transduction inhibitory molecules in family of SOCS, is mainly involved in Janus protein tyrosine kinase/signal transducer an-dantivator of transcription signaling pathway negative feedback regulation. It is involved in inflammation, oxida-tive stress, cell damage, and apoptosis. Meanwhile, it is closely related to atherosclerosis, obesity, glucose metabolism, insulin resistance, leptin, cancer, asthma, and rheumatic diseases. Therefore, SOCS-3 may become a therapeutic target of these diseases.关键词
细胞因子信号转导抑制因子3/炎症反应/信号转导/疾病Key words
suppressor of cytokine signaling 3/inflammation/signal transduction/diseases分类
医药卫生引用本文复制引用
林娜,姚晓光,李南方..细胞因子信号转导抑制因子3的研究进展[J].中国医学科学院学报,2012,34(2):178-182,5.基金项目
国家自然科学基金(31060157) （31060157）
