中国药业2012，Vol.21Issue(8)：46-47,2.
西咪替丁原料药细菌内毒素检查方法的探讨
Study on Bacterial Endotoxin Test of Cimetidine Raw Material
金艳 1王益民2
作者信息
- 1. 浙江省丽水市第二人民医院,浙江丽水,323000
- 2. 浙江省丽水市食品药品检验所,浙江丽水,323000
- 折叠
摘要
Abstract
Objective To establish a bacterial endotoxin test for cimetidine raw material. Methods According to the method of the bacteria endotoxin test in the Chinese Pharmacopoeia (edition 2010, Vol. II). Results When the mass concentration of sample was diluted to 4.0 mg/mL,no interference effect on the reaction of bacterial endotoxin and TAL was found. The limit value of the bacterial endotoxin was 0. 5 EU/mg. Conclusion It is feasible to detect the bacterial endotoxin of cimetidine raw material by the method of bacterial endotoxin test.关键词
西咪替丁/细菌内毒素检查法/干扰试验Key words
cimetidine/ bacteria endotoxin test/ interference test分类
医药卫生引用本文复制引用
金艳,王益民..西咪替丁原料药细菌内毒素检查方法的探讨[J].中国药业,2012,21(8):46-47,2.
