中国药业2012，Vol.21Issue(9)：19-21,3.
紫外分光光度法测定氟胞嘧啶片的溶出度
Dissolution Determination of Flucytosine Tablets by UV Spectrophotometry
王小兵 1刘艳 2郑静 1徐玉文1
作者信息
- 1. 山东省食品药品检验所,山东济南,250101
- 2. 山东省淄博市妇幼保健院药剂科,山东淄博,255029
- 折叠
摘要
Abstract
Objective To establish the dissolution determination method for Flucytosine Tablets by UV spectrophotometry. Methods Make sure the dissolution determination method for Flucytosine Tablets by choosing the different method,speed and dissolution solute by UV spectrophotometry. Results According to the second method of Appendix X C in the Chinese Pharmacopoeia (edition 2010), water of 1000 mL was used as the dissolution solute,kept at (37 ±0. 5)℃ ,the rotation speed was 50r/min and detected by UV spectrophotometry at the wave length of 276 nm. Conclusion This method is simple and easy,which can be used to determine the dissolution of Flucytosine Tablets.关键词
氟胞嘧啶片/溶出度/紫外分光光度法Key words
Flucytosine Tablets/dissolution/UV spectrophotometry分类
医药卫生引用本文复制引用
王小兵,刘艳,郑静,徐玉文..紫外分光光度法测定氟胞嘧啶片的溶出度[J].中国药业,2012,21(9):19-21,3.
