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遗忘型轻度认知损害脑电功率值变化分析

倪建良 杨华 孙毅 魏丽丽 陈炜

浙江医学2012,Vol.34Issue(10):793-797,5.
浙江医学2012,Vol.34Issue(10):793-797,5.

遗忘型轻度认知损害脑电功率值变化分析

Brain electrical power value in elderly with amnestic mild cognitive impairment

倪建良 1杨华 1孙毅 2魏丽丽 2陈炜2

作者信息

  • 1. 310012,杭州,浙江省立同德医院精神科
  • 2. 浙江大学医学院附属邵逸夫医院精神卫生科,浙江大学邵逸夫临床医学研究所
  • 折叠

摘要

Abstract

Objective To evaluate the application of brain electrical power value (BEPV) in assessment of elderly with amnestic mild cognitive impairment (aMCI). Methods BEPV data were recorded in 28 aMCI individuals, 24 patients with Alzheimer's disease (AD) and 20 healthy elderly individuals (HC). Results The slow waves relative powers on anterior temporal and frontal lobes significantly increased in aMCI group than those in HC group (P<0.05). Compared to aMCI and HC groups, the slow waves absolute(μV2) and relative powers (%) significantly increased in AD group(P<0.05). In addition, relative powers of a and β showed less focalization effect in AD (P<0.05). Conclusion BEPV can make a fine differentiation between aMCI and mild AD. The increased slow waves relative powers on anterior temporal and frontal lobes in aMCI may contribute to distinguishment between aMCI and HC.

关键词

遗忘型轻度认知障碍/阿尔茨海默病/脑电功率值/脑电图

Key words

Amnestic mild cognitive impairment Alzheimer's disease Brain Electrical Power Value Electroencephalogram

引用本文复制引用

倪建良,杨华,孙毅,魏丽丽,陈炜..遗忘型轻度认知损害脑电功率值变化分析[J].浙江医学,2012,34(10):793-797,5.

基金项目

浙江省科技厅重大科技专项(2007C13053) (2007C13053)

浙江省医药卫生科学研究基金计划项目(2010kyA047) (2010kyA047)

浙江省中医药科技计划项目(2009CB044) (2009CB044)

浙江医学

OACSTPCD

1006-2785

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