浙江医学2012，Vol.34Issue(10)：798-801,4.
急性脑梗死患者认知功能、脑白质损伤的评定及相关性研究
Assessment of cognitive function in patients with acute brain infarction and its correlation with white matter lesions
王翠棉 1刘红 1任王芳 1梁冬青 1陈国钱 1张旭1
作者信息
- 1. 325000,温州医学院附属第一医院神经内科
- 折叠
摘要
Abstract
Objective To assess the cognitive function in patients with acute brain infarction and its correlations with white matter lesions. Methods The cognitive status were assessed in 88 patients with acute brain infarction by Mini-Mental Status Examination, (MMSE) and Montreal Cognitive Assessment(MoCA); the assessments by Fazekas scale and cholinergic pathways hyperintensities scale (CHIPS) were performed in patients undergoing cranial MRI scanning. Results The cognitive abnormality was detected in 83 cases (94.3%) by MoCA; meanwhile it was detected in 22 cases (25.0%) by MMSE. According to MoCA assessment, there were significant differences in total score, visuospatial/executive abilities, naming, abstract, language, delayed memory between patients with cognitive abnormality and those with normal cognition (P<0.05). The scores of MoCA were negatively correlated with the Fazekas and CHIPS scores (r=-0.340, P=0.001; r=-0.343, P=0.001). Conclusion MoCA is more sensitive than MMSE in screening cognitive impairment after acute brain infarction; and there are negative correlations of cognitive function with the severity of white matter lesion and cholinergic pathway lesions in white matter.关键词
脑梗死/认知损害/脑白质损伤/量表Key words
Brain infarction Cognitive impairment White matter lesion Assessment引用本文复制引用
王翠棉,刘红,任王芳,梁冬青,陈国钱,张旭..急性脑梗死患者认知功能、脑白质损伤的评定及相关性研究[J].浙江医学,2012,34(10):798-801,4.
