浙江医学2012,Vol.34Issue(10):802-805,4.
血清RBP4及超敏CRP在2型糖尿病合并冠心病中的作用研究
Serum RBP4 and hs-CRP levels in patients with type 2 diabetes mellitus complicated with coronary heart disease
王建友 1陈华 2朱敏敏1
作者信息
- 1. 325608,乐清市第二人民医院检验科
- 2. 325608,乐清市第二人民医院内分泌科
- 折叠
摘要
Abstract
Objective To investigate serum retinol binding protein 4 (RBP4) and high sensitive C-reactive protein (hs-CRP) levels in patients of type 2 diabetes mellitus (T2DM) complicated with coronary heart disease (CHD) and the clinical significance. Methods Serum sample were taken from 35 patients of T2DM with CHD, 37 patients with T2DM and 35 normal controls. RBP4 was measured with ELISA, and hs-CRP was measured with immune nephelometry. Results The patients of T2DM with CHD had significantly higher levels of RBP4 and hs-CRP than those of T2DM patients and normal controls (all P< 0.05), serum RBP4 levels were positively correlated with hs-CRP levels (r= 0.342, P<0.05). Conclusion Patients of T2DM complicated with CHD have high serum levels of RBP4 and hs-CRP, which may be involved in the development of these two diseases.关键词
视黄醇结合蛋白4/超敏C反应蛋白/2型糖尿病/冠状动脉心脏病Key words
Retinol binding protein 4 High sensitive C-reactive protein Type2 diabetes mellitus Coronary heart disease引用本文复制引用
王建友,陈华,朱敏敏..血清RBP4及超敏CRP在2型糖尿病合并冠心病中的作用研究[J].浙江医学,2012,34(10):802-805,4.