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舒血宁治疗慢性精神分裂症经颅多普勒检测对照研究

王鹤秋 顾成宇 任志斌 陈松

浙江医学2012,Vol.34Issue(11):888-890,3.
浙江医学2012,Vol.34Issue(11):888-890,3.

舒血宁治疗慢性精神分裂症经颅多普勒检测对照研究

A case-control study of the Measurement of Transcranial Doppler System (TCD) and SANS among 120 Chronic Schizophrenia in-hospital patients treated with Shu Xuening

王鹤秋 1顾成宇 1任志斌 1陈松1

作者信息

  • 1. 310012,浙江省立同德医院精神卫生科
  • 折叠

摘要

Abstract

Objective To observe the character of the blood-flow of the basicranial arteries and the effect with shuxuen-ing in negative schizophrenic patients. Methods 120 in-hospital schizophrenic patients were involved in the average blood flow in postcranial arteries (Vm) measurement as well as being assessed with SANS. The 120 patients were divided into group A and B, patients in group A were treated with antipsychotics and 12ml shuxuening dripping each day, while patients in group B took antipsychotics only. All the patients were measured by TCD and SANS and were compared between and within the groups. Results Patients with schizophrenia had abnormal appearance in TCD and the Vm scores decreased. After 8 weeks' therapy with shuxuening, group A patients got improvement in TCD results, the MCA, ACA, PCA and BA results in the arteries has statistical difference (p<0.05); while the VA results changed little. What is more, negative chronic schizophrenic patients have lower blood-flow in postcranial arteries. In group A, the Vm results were enhanced after the patients were treated with shuxuening and the blood flow was faster than that of Group B, which has a significant difference (p<0.05). The scores of group A in SANS declined statistically. Conclusion Treated with the combination of antipsychotics and shuxuening, the in-hospital chronic schizophrenic patients get more remission in negative symptoms and more blood flow in postcranial arteries.

关键词

舒血宁/慢性精神分裂症/脑平均血流速度/阴性症状

Key words

Shu Xuening/ Chronic schizophrenia/ average blood flow in postcranial arteries/ Negative symptoms

引用本文复制引用

王鹤秋,顾成宇,任志斌,陈松..舒血宁治疗慢性精神分裂症经颅多普勒检测对照研究[J].浙江医学,2012,34(11):888-890,3.

浙江医学

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1006-2785

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